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The most common skin manifestations include a pale, washed-out complexion from anemia, dryness and cracking (particularly at the corners of the mouth), hyperpigmented patches on the hands or face, and glossitis a swollen, smooth, unusually red tongue

Strategies that support microbial diversity, including probiotic supplementation (particularly Lactobacillus and Bifidobacterium strains studied in atopic conditions), prebiotic fiber intake, and avoidance of unnecessary antibiotics, create a more favorable environment for peptide interventions

Mitophagy is the selective degradation of damaged or excessive mitochondria by an autophagic pathway 59,60

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After 24 hours, viral supernatant was collected, filtered through a 0.45-m cellulose acetate filter and used to infect freshly thawed HeLa cells